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  • Title: New linear polyamine derivatives in spider venoms.
    Author: Tzouros M, Chesnov S, Bienz S, Hesse M, Bigler L.
    Journal: Toxicon; 2005 Sep 01; 46(3):350-4. PubMed ID: 15982700.
    Abstract:
    Linear free polyamines were characterized in the venom of the spiders Agelenopsis aperta, Hololena curta, and Paracoelotes birulai by RP-HPLC coupled to mass spectrometry. The several linear polyamines found were tetramine, pentamine, and hexamine derivatives. Some of these natural products were identified as N-hydroxylated, guanidylated, or acetylated compounds. In addition, the biosynthetical pathway leading to the formation of acylpolyamines in spider venoms is discussed.
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