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  • Title: Molecular cloning of a novel adenosine receptor gene from rat brain.
    Author: Chern Y, King K, Lai HL, Lai HT.
    Journal: Biochem Biophys Res Commun; 1992 May 29; 185(1):304-9. PubMed ID: 1599465.
    Abstract:
    We have isolated an adenosine receptor gene (RA2) from a rat brain cDNA library. This novel rat adenosine receptor has 410 amino acids, as deduced from its base sequence, and shows 82% amino acid identity with the dog A2 receptor. Amino acid sequence analysis indicates that RA2 protein contains seven transmembrane domains and belongs to the G protein-coupled receptor family. The variations in amino acid sequences between RA2 protein and the dog A2 receptor are largely confined to the extracellular second loop and the carboxyl terminus.
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