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  • Title: Antibacterial caged-tetraprenylated xanthones from the fruits of Garcinia hanburyi.
    Author: Sukpondma Y, Rukachaisirikul V, Phongpaichit S.
    Journal: Chem Pharm Bull (Tokyo); 2005 Jul; 53(7):850-2. PubMed ID: 15997152.
    Abstract:
    A new caged-tetraprenylated xanthone, hanburinone (1), was isolated from the fresh fruits of Garcinia hanburyi together with four known caged-tetraprenylated xanthones; isomoreollin B (2), morellin (3), moreollic acid (4) and morellic acid (5). Their structures were elucidated by analysis of spectroscopic data and comparison of the NMR data with those reported previously. Compounds 4 and 5 showed moderately antibacterial activity against methicillin-resistant Staphylococcus aureus with a MIC value of 25 microg/ml.
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