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Title: Amphiphile-induced tubular budding of the bilayer membrane. Author: Kralj-Iglic V, Hägerstrand H, Veranic P, Jezernik K, Babnik B, Gauger DR, Iglic A. Journal: Eur Biophys J; 2005 Nov; 34(8):1066-70. PubMed ID: 15997398. Abstract: Amphiphile-induced tubular budding of the erythrocyte membrane was studied using transmission electron microscopy. No chiral patterns of the intramembraneous particles were found, either on the cylindrical buds, or on the tubular nanoexovesicles. In agreement with these observations, the tubular budding may be explained by in-plane ordering of anisotropic membrane inclusions in the buds where the difference between the principal membrane curvatures is very large. In contrast to previously reported theories, no direct external mechanical force is needed to explain tubular budding of the bilayer membrane.[Abstract] [Full Text] [Related] [New Search]