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  • Title: Enhanced oral bioavailability of breviscapine after encapsulation in a liposomal formulation.
    Author: Zhong HJ, Deng YJ, Yang BH, Li CL, Du S.
    Journal: Pharmazie; 2005 Jun; 60(6):475-6. PubMed ID: 15997842.
    Abstract:
    This report firstly describes the pharmacokinetic study of liposomal breviscapine (LB) after oral administration in rats. The mean Cmax and AUC(0-->t) of LB were 3.3 and 3.1-fold higher than those of breviscapine solution (BS). The oral absorption of breviscapine was significantly increased after encapsulation in the liposomal formulation.
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