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  • Title: The effects of intraocular gases on rabbit blood-retinal barrier permeability.
    Author: Green K, Slagle T, Cheeks L, Norman BC.
    Journal: Lens Eye Toxic Res; 1992; 9(1):67-76. PubMed ID: 1599908.
    Abstract:
    The effects of intravitreal expansile gases, sulfur hexafluoride and octafluoropropane, as well as air and needle insertion alone were assessed by iris fluorescein angiography and blood-retinal barrier permeability determination. Iris angiography, at 3 days after injection, indicated no differences between experimental and paired control eyes. Vitreous fluorophotometry on day 1, day 4 and day 7 after gas or sham injection also showed no differences between paired control and experimental eyes regardless of which experimental condition was employed. The results indicate that these gases are non-toxic to the blood-retinal barrier over a 7 day time course.
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