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  • Title: Attachment of periodontal ligament cells onto various antibiotics-loaded GTR membranes.
    Author: Hung SL, Lin YW, Chen YT, Ling LJ.
    Journal: Int J Periodontics Restorative Dent; 2005 Jun; 25(3):265-75. PubMed ID: 16001739.
    Abstract:
    This study compared the natures of various guided tissue regeneration (GTR) membranes impregnated with amoxicillin or tetracycline. Whether the antibiotics-loaded membranes enhance the attachment of the periodontal ligament cells in the presence of oral pathogens was further analyzed. S mutans and A actinomycetemcomitans diminished the attachment of periodontal ligament cells onto the membranes as evaluated by SEM analysis. These bacterial effects on cellular attachment could be reversed using the antibiotics-loaded membranes. The information obtained in this study is valuable for the future application of antibiotics-loaded membranes during GTR therapy.
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