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  • Title: Early composite cranioplasty in infants with severe aplasia cutis congenita: a report of two cases.
    Author: Ploplys EA, Muzaffar AR, Gruss JS, Ellenbogen RG.
    Journal: Cleft Palate Craniofac J; 2005 Jul; 42(4):442-7. PubMed ID: 16001928.
    Abstract:
    OBJECTIVE: Severe cutis aplasia congenita has traditionally been treated with initial soft tissue coverage and delayed cranioplasty. We advocate the technique of early composite reconstruction of both bone and soft tissues. METHODS: Two cases of cutis aplasia congenita with large skull defects (6 x 10 cm, 8 x 8 cm) of superficial layers, skull, and dura are presented. In each case, composite reconstruction was undertaken before 2 weeks of age with restoration of bony and soft tissue coverage through autologous, full-thickness cranial bone grafts and scalp flaps. Both children have been followed up over 2 years with clinical examination and computed tomography (CT) scans. RESULTS: In both cases, defects were completely repaired postoperatively and remained closed 2 years later. Complete regeneration of calvarial bone graft donor sites were documented by CT scan. Head shape and circumference were normal at 2-year follow up.
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