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  • Title: Early effect of exogenous Na hyaluronate on mucociliary clearance.
    Author: Yildirim A, Turgut B, Bebek AI, Gumus C, Kocaturk S, Kunt T.
    Journal: Am J Rhinol; 2005; 19(3):244-7. PubMed ID: 16011128.
    Abstract:
    BACKGROUND: An animal study is performed to determine the early effect of 1% Na hyaluronate on mucociliary clearance function. METHODS: One percent of Na hyaluronate was introduced into the maxillary sinuses of rabbits by anterior antrostomy. A physiological solution of 1% NaCl was introduced into the maxillary sinuses of a control group to equalize the influence of Na for both groups. The treatment material was sprayed with an atomizer for coating the maxillary sinus lining. Technetium-99m diethylenetriamine pentaacetate dynamic scintigraphic imaging was performed to evaluate mucociliary clearance function on all rabbits 72 hours after the surgical procedure. RESULTS: Although the mean rate of mucociliary clearance of the Na hyaluronate group was slightly worse than the control group; there was no statistically significant difference between them. CONCLUSION: There is no early effect of exogenous 1% Na hyaluronate on mucociliary clearance function.
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