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  • Title: Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.
    Author: Femiano F, Gombos F, Scully C.
    Journal: J Oral Pathol Med; 2005 Aug; 34(7):423-5. PubMed ID: 16011612.
    Abstract:
    BACKGROUND: The objective of this study was to investigate the effect of zinc on recurrent herpes labialis. MATERIALS/METHODS: Twenty patients (12 females; median age 26.6 years) with a history of recurrent herpes labialis >6 episodes each year were treated with systemic zinc sulphate 22.5 mg twice daily for the months of February, March, September and October. All patients were followed for 12 months. RESULTS: Herpetic lesions reduced to <4 episodes (average 3) for the 12 months and the duration was <7 days for each episode (average 5.7). CONCLUSIONS: Systemic zinc sulphate appeared to reduce both the number of episodes and the time to recovery of herpes labialis.
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