These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Revisiting the armed-disarmed concept rationale: s-benzoxazolyl glycosides in chemoselective oligosaccharide synthesis.
    Author: Kamat MN, Demchenko AV.
    Journal: Org Lett; 2005 Jul 21; 7(15):3215-8. PubMed ID: 16018624.
    Abstract:
    [reaction: see text]. It has been discovered that 2-O-benzyl-3,4,6-tri-O-acyl SBox glycosides are significantly less reactive than even "disarmed" peracylated derivatives. This finding has been applied to the synthesis of various oligosaccharides, the monomeric units of which are connected via cis-cis, trans-cis, and cis-trans sequential glycosidic linkages. Two-stage activation of the armed (benzylated) donor over moderately (dis)armed (acylated) and, subsequently, over disarmed (2-O-benzyl-3,4-O-diacylated) acceptor has also proven to be feasible.
    [Abstract] [Full Text] [Related] [New Search]