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  • Title: Carbimazole induced eosinophilic granulomatous vasculitis localized to the stomach.
    Author: Sève P, Stankovic K, Michalet V, Vial T, Scoazec JY, Broussolle C.
    Journal: J Intern Med; 2005 Aug; 258(2):191-5. PubMed ID: 16018796.
    Abstract:
    Vasculitis associated with anti-neutrophil cytoplasmic antibodies has been reported in patients treated with anti-thyroid drugs and especially propylthiouracil. We report here a case of granulomatous eosinophilic vasculitis mimicking gastric neoplasm and peripheral eosinophilia in a 27-year-old man who was treated with carbimazole for 5 months for Graves' disease. Clinical and morphologic features resolved within 2 months after stopping the drug, suggesting a causative role for the drug. To our knowledge, this is the first biopsy-proven granulomatous eosinophilic vasculitis associated with this drug.
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