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  • Title: Topical streptococcal preparation, OK-432, for atopic dermatitis.
    Author: Horiuchi Y.
    Journal: J Dermatolog Treat; 2005 Apr; 16(2):117-20. PubMed ID: 16019627.
    Abstract:
    Effective treatment of atopic dermatitis (AD) may in some cases prove quite difficult. OK-432, prepared from the penicillin-treated Su strain of type III Group A Streptococcus pyogenes, has been shown to be effective for treating not only cancer but verruca vulgaris as well, suggesting this agent to create the Th1 pathway through IL-12 induction. Four AD patients consented to trial use of the OK-432 ointment. OK-432 was found to bring about complete cure in the present four cases. Based on results from its use, OK-432 may be concluded to be highly effective for treating AD.
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