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  • Title: A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis.
    Author: Brion M, Dupuy BM, Heinrich M, Hohoff C, Hoste B, Ludes B, Mevag B, Morling N, Niederstätter H, Parson W, Sanchez J, Bender K, Siebert N, Thacker C, Vide C, Carracedo A.
    Journal: Forensic Sci Int; 2005 Oct 29; 153(2-3):103-8. PubMed ID: 16024201.
    Abstract:
    A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.
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