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  • Title: [A case of malignant pleural mesothelioma with osseous and cartilaginous formation].
    Author: Yoshii C, Imai S, Hoshino H, Sugaya H, Mizutani Y, Iwaki H, Enomoto K.
    Journal: Nihon Kyobu Shikkan Gakkai Zasshi; 1992 Feb; 30(2):338-42. PubMed ID: 1602665.
    Abstract:
    A 85-year-old man was admitted to our unit on November 17, 1989 with bloody sputum and abnormal shadow on chest X-ray film. Chest X-ray and CT on admission showed a large tumor mass approximately 9 cm in diameter in the right middle and lower lung field. Microscopic examination of the needle biopsy specimen from the tumor revealed biphasic malignant pleural mesothelioma. After admission, thoracentesis was performed, because of rapidly increasing right-sided pleural effusion. One of the two trochar catheter was inadvertently inserted in the tumor. Tumor tissue obtained through the catheter showed malignant mesothelioma with osseous and cartilaginous formation. Only isolated reports by Goldstein and Yousem have reported osseous and catilaginous differentiation in malignant mesothelioma. To our knowledge, this is the first reported case in Japan.
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