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  • Title: Noninvasive ventilation options in pediatric myasthenia gravis.
    Author: Piastra M, Conti G, Caresta E, Tempera A, Chiaretti A, Polidori G, Antonelli M.
    Journal: Paediatr Anaesth; 2005 Aug; 15(8):699-702. PubMed ID: 16029407.
    Abstract:
    A 10-month-old female infant with congenital myasthenic syndrome suffering from acute respiratory failure was supported using face mask positive pressure ventilation until definitive diagnosis and specific treatment was achieved. A 12-year-old girl suffering from seronegative myasthenia gravis was treated by helmet-delivered noninvasive ventilation during recurrent myasthenic episodes. Noninvasive support was really beneficial in the myasthenic crisis with respiratory muscle weakness, whereas a shift to tracheal intubation was necessary when pulmonary infection and multiple atelectasis occurred. The new helmet interface for noninvasive positive pressure ventilation can represent a valuable means of respiratory support in the early phase of respiratory failure in older children.
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