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  • Title: Serratia marcescens prosthesis infection successfully treated with meropenem after imipenem failure.
    Author: Lefort A, Righi S, Jauréguy F, Bégué T, Robineau M, Bouchaud O, Lortholary O.
    Journal: J Infect; 2005 Aug; 51(2):E45-7. PubMed ID: 16038749.
    Abstract:
    A 78-year-old woman developed an early knee-prosthesis infection due to multiresistant Serratia marcescens that was successfully treated with high-dose meropenem, after failure of a long-term therapy combining imipenem and multiple surgical interventions. Because of its lower neurotoxicity, meropenem might be preferred to imipenem/cilastatin for the treatment of osteo-articular infections due to multiresistant Gram-negative bacilli in the elderly.
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