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  • Title: On the road to bioremediation of "dioxin".
    Author: Buckel W.
    Journal: Chem Biol; 2005 Jul; 12(7):723-4. PubMed ID: 16039520.
    Abstract:
    Mohammadi and Sylvestre report engineering of a dioxygenase to create an enzyme that attacks dibenzofuran in the lateral position. Subsequent oxidation and a second dioxygenation produced ring-open products. All metabolites were unambiguously identified by 1H-NMR. This new pathway targets degradation of chlorinated dibenzofurans.
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