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  • Title: Synthesis and biological activity of novel acridinylidene and benzylidene thiazolidinediones.
    Author: Mourão RH, Silva TG, Soares AL, Vieira ES, Santos JN, Lima MC, Lima VL, Galdino SL, Barbe J, Pitta IR.
    Journal: Eur J Med Chem; 2005 Nov; 40(11):1129-33. PubMed ID: 16040159.
    Abstract:
    A novel set of acridinylidene thiazolidinediones and benzylidene thiazolidinediones was synthesized by nucleophilic addition of cyanoacrylates. Some of these compounds were evaluated for their glucose lowering capability and their effects on the triglyceride level in alloxan diabetic mice.
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