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  • Title: Acute painful neuropathy in thallium poisoning.
    Author: Kuo HC, Huang CC, Tsai YT, Chu CC, Hsieh ST, Chu NS.
    Journal: Neurology; 2005 Jul 26; 65(2):302-4. PubMed ID: 16043805.
    Abstract:
    Dysesthesia, allodynia, distal muscle weakness, and sensory impairment were noted in two patients with acute thallium intoxication. Two months later, nerve conduction studies showed an axonal degeneration. Sural nerve biopsy disclosed a decreased fiber density in the large myelinated fibers. Quantitative sensory testing also revealed an impairment of pinprick, temperature, and touch sensations. Cutaneous nerve biopsy confirmed a loss of epidermal nerves indicating an involvement of the small sensory nerves.
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