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Title: Heartburn and multiple-site foregut perforations as primary manifestation of Crohn's disease. Author: Bona D, Incarbone R, Chella B, Vecchi M, Bonavina L. Journal: Dis Esophagus; 2005; 18(3):199-201. PubMed ID: 16045583. Abstract: Crohn's disease may affect any segment of the digestive tract, more commonly the distal ileum, colon and/or perianal region. There is an increasing number of reports dealing with foregut Crohn's disease. We present the case of a patient with a history of heartburn and multiple spontaneous perforations of the esophagus, duodenum and jejunum as a primary manifestation of Crohn's disease who required emergency surgical and endoscopic procedures. Early detection of Crohn's disease may decrease the incidence of acute life-threatening complications provided that appropriate medical treatment is administered and a multidisciplinary approach is offered to these patients.[Abstract] [Full Text] [Related] [New Search]