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  • Title: Ketogenic diet increases calbindin-D28k in the hippocampi of male ICR mice with kainic acid seizures.
    Author: Noh HS, Kang SS, Kim DW, Kim YH, Park CH, Han JY, Cho GJ, Choi WS.
    Journal: Epilepsy Res; 2005 Jul; 65(3):153-9. PubMed ID: 16046100.
    Abstract:
    The ketogenic diet (KD) increased the expression of calbindin-D(28k) (CB) in the interneurons of the hippocampus compared with the normal diet (ND)-fed mice. Also, 2 days after kainic acid (KA) administration, numerous CB-expressing astrocytes were found in the KD-fed mice compared with those of the ND-fed mice. These results suggest that the neuroprotective effect of the KD on the KA-induced toxicity may be, in part, mediated via an increased expression of CB.
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