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  • Title: Targeting malaria parasite proteins to the erythrocyte.
    Author: Templeton TJ, Deitsch KW.
    Journal: Trends Parasitol; 2005 Sep; 21(9):399-402. PubMed ID: 16046185.
    Abstract:
    The intraerythrocytic stages of the protozoan parasite Plasmodium falciparum reside within a parasitophorous vacuole (PV) and set up unique "extraparasite, intraerythrocyte" protein-trafficking pathways that target parasite-encoded proteins to the erythrocyte cytoplasm and cell surface. Two recent articles report the identification of trafficking motifs that regulate the transport of parasite-encoded proteins across the PV. These articles greatly aid the annotation of the parasite "secretome" catalog of proteins that are targeted to the erythrocyte cytoplasm or cell membrane.
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