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  • Title: [Changes of adrenal cortex structure in young rats under the single influence of hypobaric hypoxia].
    Author: Chipashvili NM.
    Journal: Georgian Med News; 2005 Jun; (123):50-3. PubMed ID: 16052057.
    Abstract:
    Histo- and ultrastructure investigation of adrenal cortex in young animals after the single administration of hypobaric hypoxia has been carried out. Hypobaric hypoxia was modeled in ventilated barocamera with pO(2) decreasing till 364-372 mm Hg on the 15 albino male rats 51-120 days of age and 90-120 gr of body mass. Duration of the experiment was 4+/-1 hours. The animals of the control group were placed in normobaric conditions for the same time. Adrenocorticocytes of z. fasciculate are more sensible to oxygen insufficiency. Hyperchromocitous and shrinking of nucle-decrease of lipids, mitochondrion swelling and diffuse cells edema are presented. Myelin like transformation of lipids drops are remarkable. Hypobaric hypoxia is a severe stress-factor, which induces remarkable structure failure in adrenal cortex, especially in z. facsiculata.
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