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  • Title: Nonoccupational determinants of plasma DDT and p,p'-DDE in men from Chiapas, Mexico.
    Author: Barraza-Villarreal A, Farías P, Díaz Sánchez V, Bailey JL, De Jager T, Ayotte P, Hernández-Avila M, Dewailly E.
    Journal: Arch Environ Health; 2004 Jan; 59(1):42-9. PubMed ID: 16053209.
    Abstract:
    A cross-sectional study was conducted to evaluate nonoccupational biological exposure to 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) compounds and to identify the main factors associated with such exposure in a malaria endemic region in Mexico. Capillary gas column chromatography was used to determine levels of p,p'-DDT and its metabolites in plasma. The mean age of the 144 male participants was 28 yr. Mean p,p'-DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene) and p,p'-DDT levels were 203.5 microg/l and 67.4 microg/l, respectively. Those whose houses had been sprayed for malaria control had much higher p,p'-DDE levels (p < 0.001). High levels of chlorinated pesticides were found despite being banned in Mexico for agricultural and public health use. Findings demonstrate the role of antimalarial campaigns as a major contributing factor for high DDT plasma levels.
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