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  • Title: The prevalence of osteoarthrosis in cases of advanced internal derangement of the temporomandibular joint: a clinical, surgical and histological study.
    Author: Dimitroulis G.
    Journal: Int J Oral Maxillofac Surg; 2005 Jun; 34(4):345-9. PubMed ID: 16053840.
    Abstract:
    INTRODUCTION: The articular disk has a central role in the pathology of internal derangement of the Temporomandibular Joint (TMJ). What is less clear is the role of osteoarthrosis in the development of internal derangement. The aim of this study is to determine the prevalence of osteoarthrosis in cases of advanced and recalcitrant TMJ internal derangement that were treated by diskectomy. MATERIALS AND METHODS: This study involved 22 joints in 18 patients who underwent surgery for the treatment of advanced and recalcitrant internal derangement of the TMJ. All patients included in the study failed to respond to at least 6 months of pre-operative conservative treatment and the clinical diagnoses of advanced TMJ internal derangement were confirmed on pre-operative MRI's. Tissue specimens were obtained from all 22 joints for histopathology. The specimens included articular disks that were excised from all 22 joints which were found to have severely displaced and deformed disks that were judged to be irreparable at the time of surgery. Also included were eight tissue samples from the mandibular condyles that were judged to be diseased on pre-operative tomograms and at the time of surgery. All samples were prepared in serial sections in the standard way and examined under light microscopy by two experienced Oral Pathologists. RESULTS: There were 22 specimens of articular disk examined together with 8 specimens from the mandibular condyle. All 22 joints (100%) showed histological evidence of disk pathology and eight of the 22 joints (34.4%) were found to have condylar pathology. The most common disk pathology was hyalinization indicative of disk degeneration (12/22). The most common condylar pathology found was articular surface degeneration indicative of osteoarthrosis (8/22). CONCLUSION: The clinical and radiological diagnoses of advanced TMJ internal derangement correlated with histological findings of degeneration and inflammation of the articular disk in all 22 specimens. The 8 specimens obtained from the condylar head showed histological features consistent with osteoarthrosis. This study showed that osteoarthrosis and internal derangement were found to co-exist in the same joint in about one-third of cases. The fact that osteoarthrosis was not found in all cases suggests that perhaps the widely held view that subclinical osteoarthrosis may lead to pathologic tissue responses in the form of internal derangement will need to be re-examined.
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