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  • Title: Nonsteroidal anti-inflammatory drugs for rheumatoid arthritis during pregnancy.
    Author: Florescu A, Koren G.
    Journal: Can Fam Physician; 2005 Jul; 51(7):961-2. PubMed ID: 16060172.
    Abstract:
    QUESTION: I am treating two pregnant patients who have rheumatoid arthritis with nonsteroidal anti-inflammatory drugs. Are these medications safe at high doses during pregnancy? ANSWER: While these medications do not appear to increase overall rates of congenital malformations, they do increase the risk of ductus arteriosus constriction or closure. QUESTION: Je traite deux patientes enceintes qui souffrent d’arthrite rhumatoïde avec des anti-inflammatoires non stéroïdiens. Ces médicaments sont-ils sûrs à fortes doses durant la grossesse? RÉPONSE: Il ne semble pas que ces médicaments augmentent les taux globaux de malformations congénitales mais ils accroissent effectivement le risque de constriction ou d’obstruction du canal artériel.
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