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  • Title: [Histochemical characteristics of adrenergic myocardial and adrenal fibers in experimental narrowing of the aorta and pulmonary artery].
    Author: Mishnev OD, Tverskaia MS, Karpova VV, Chumakova MA, Izmaĭlova NS, Kadyrova MKh, Abdulkerimova NZ, Kliuchikova VIu.
    Journal: Arkh Patol; 2005; 67(3):21-4. PubMed ID: 16075607.
    Abstract:
    Ligation of the aorta or the pulmonary trunk was the method of experimental overloading of heart ventricles. Histochemical studies indicated activation of mediator chain of the sympatho-adrenal system. Catecholamines content in the nervous plexus of the overloaded ventricle did not change but there was an increase of their content in the medullary layer of the adrenals. Thus, chromaffin cells activity increases and desympathization of the heart muscle may be an important step in pathogenesis of heart failure in acute arterial hypertension.
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