These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Homology, disruption and phenotypic analysis of CaGS Candida albicans gene induced during macrophage infection.
    Author: Luongo M, Porta A, Maresca B.
    Journal: FEMS Immunol Med Microbiol; 2005 Sep 01; 45(3):471-8. PubMed ID: 16084700.
    Abstract:
    During macrophage infection Candida albicans expresses differentially several genes whose functions are associated with its survival strategy. Among others, we have isolated CaGS gene, which is homologous to SNF3, a glucose sensor of Saccharomyces cerevisiae. To elucidate its potential role during infection, CaGS has been disrupted and the resulting phenotype analyzed on different solid media. The null mutant lost the ability to form hyphae on a medium with low glucose concentration and serum. Furthermore, this mutant does not disrupt macrophage in in vitro infections. We believe that this putative glucose sensor is involved in hyphal development during macrophage infection.
    [Abstract] [Full Text] [Related] [New Search]