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Title: MicroRNAs: Loquacious speaks out. Author: Leuschner PJ, Obernosterer G, Martinez J. Journal: Curr Biol; 2005 Aug 09; 15(15):R603-5. PubMed ID: 16085484. Abstract: In Drosophila, Dicer-2 requires the double-stranded RNA binding protein R2D2, to mediate the assembly of short interfering RNAs into the RNA-induced silencing complex. New data show that Dicer-1 also requires a double-stranded RNA binding protein called Loquacious for efficient microRNA-mediated gene silencing.[Abstract] [Full Text] [Related] [New Search]