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  • Title: Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum.
    Author: Mosel DD, Dumitru R, Hornby JM, Atkin AL, Nickerson KW.
    Journal: Appl Environ Microbiol; 2005 Aug; 71(8):4938-40. PubMed ID: 16085901.
    Abstract:
    Concentrations of (E,E)-farnesol needed to inhibit germ tube formation were determined for Candida albicans strains A72 and SC5314 by using six different conditions known to trigger germination. For defined media, 1 to 2 microM farnesol was sufficient. However, with serum at 2 to 20%, up to 250 microM farnesol was required. Farnesol blocked germ tube formation but did not block elongation of existing germ tubes.
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