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  • Title: Post-transplant multiple myeloma in a pediatric renal transplant patient.
    Author: Tcheng WY, Said J, Hall T, Al-Akash S, Malogolowkin M, Feig SA.
    Journal: Pediatr Blood Cancer; 2006 Aug; 47(2):218-23. PubMed ID: 16086426.
    Abstract:
    Post-transplant lymphoproliferative disease (PTLD) is a well-recognized complication of the intense immunosuppression required in solid organ and bone marrow transplant recipients. The clinical presentation is varied and can range from a benign infectious mononucleosis-like syndrome to malignant lymphoma. PTLD manifesting as multiple myeloma occurs rarely. We report the unique occurrence of Epstein-Barr virus (EBV)-associated post-transplant multiple myeloma in a 16-year-old male. In contrast to previously described cases of PTLD-myeloma type, this patient was very young, had a clear association with EBV, and an indolent clinical course.
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