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Pubmed for Handhelds
PUBMED FOR HANDHELDS
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Title: Chronic inflammatory demyelinating polyradiculoneuropathy with tumefactive central demyelination. Author: Krivickas LS, Hochberg FH, Freeman S. Journal: Muscle Nerve; 2006 Feb; 33(2):283-8. PubMed ID: 16086427. Abstract: A 46-year-old man with a 1-year history of distal paresthesias and mild distal weakness subacutely developed paralysis of the left hand. Electrodiagnostic evaluation revealed a demyelinating peripheral neuropathy that met criteria for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Magnetic resonance imaging of the brain revealed a mass that enhanced with contrast, but revealed focal myelin loss with intense macrophage activity and axonal preservation on biopsy. The mass and hand weakness improved following steroid therapy. The combination of CIDP and central demyelination with mass effect broadens the spectrum of demyelinating disease in association with CIDP.[Abstract] [Full Text] [Related] [New Search]