These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The upstream area of the chicken alpha-globin gene domain is transcribed in both directions in the same cells.
    Author: Borunova V, Iarovaia OV, Vassetzky YS, Razin SV.
    Journal: FEBS Lett; 2005 Aug 29; 579(21):4746-50. PubMed ID: 16098523.
    Abstract:
    It was demonstrated previously that in erythroid chicken cells an extended upstream area of the alpha-globin gene domain is transcribed in both directions as a part of ggPRX gene and a part of a full domain transcript of the alpha-globin gene domain. Here, we show that both DNA chains of the above-mentioned region are transcribed in the same cells and that the corresponding transcripts coexist in nuclei. The data obtained suggest that cells possess a molecular mechanism which in some cases prevents the formation of dsRNA and subsequent destruction of both transcripts in spite of the presence of complementary RNA chains in the cell nucleus.
    [Abstract] [Full Text] [Related] [New Search]