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  • Title: [Premixed 50% nitrous oxide and oxygen: theoretical recalls and practical modalities].
    Author: Boulland P, Favier JC, Villevieille T, Allanic L, Plancade D, Nadaud J, Ruttimann M.
    Journal: Ann Fr Anesth Reanim; 2005 Oct; 24(10):1305-12. PubMed ID: 16099128.
    Abstract:
    The concept of premixed 50% nitrous oxide and oxygen dated back to 1961 in England, where it is commercialised under the name Entonox. In France, after a so marginal use, premixed 50% nitrous oxide and oxygen now knows such a revival since we first consider the pain provoked by the cure. To use correctly premixed 50% nitrous oxide and oxygen, we need to know the main properties of the nitrous oxide. The four commercial versions, now on the market, are presented (Kalinox, Medimix, Antasol, Oxynox. Except a few contraindications, these indications are large, as well at hospital as outside. In less than 10% of the cases, side effects are possible. Conditions of administration are given in details. The limits of the technic and the particular precautions of use are precised.
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