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  • Title: [Beta-radiation as adjuvant treatment of in-stent restenosis in coronary vessels].
    Author: Maeng M, Tanderup K, Jessen KA, Krusell LR, Thuesen L.
    Journal: Ugeskr Laeger; 2005 Aug 15; 167(33):3033-6. PubMed ID: 16109245.
    Abstract:
    INTRODUCTION: The purpose of this study was to describe our initial "real-world" experience with vascular b-radiation for in-stent restenosis using a simple angioplasty approach without stent implantation. MATERIALS AND METHODS: Thirty-five consecutive patients with in-stent restenosis were treated with balloon angioplasty (n = 28), cutting balloon angioplasty (n = 3), or angioplasty plus stent implantation (only in case of significant dissection: n = 4), followed by catheter-based beta-radiation. Angiographic follow-up was performed after 6 to 10 months. RESULTS: One patient experienced a left main stem occlusion immediately after beta-radiation, which necessitated an acute coronary bypass operation. No other complications related to the radiation procedure were observed. In-stent restenosis recurred in 6 of the 34 patients (18%). DISCUSSION: Our results indicate that catheter-based radiation can be safely introduced at centres without previous experience with this treatment modality. Furthermore, the in-stent restenosis recurrence rates after catheter-based radiation which have been obtained in randomised trials can be reproduced in consecutive patients.
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