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  • Title: OpsX from Haemophilus influenzae represents a novel type of heptosyltransferase I in lipopolysaccharide biosynthesis.
    Author: Gronow S, Brabetz W, Lindner B, Brade H.
    Journal: J Bacteriol; 2005 Sep; 187(17):6242-7. PubMed ID: 16109967.
    Abstract:
    The inner core region of the lipopolysaccharide (LPS) of Haemophilus influenzae is characterized by the presence of a phosphorylated 3-deoxy-alpha-D-manno-octulosonic acid (Kdo). In this study, we show that the heptosyltransferase I adding the first L-glycero-D-manno-heptose residue to this acceptor is encoded by the gene opsX, which differs in substrate specificity from the other heptosyltransferase I, known as WaaC.
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