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  • Title: TLR ignores methylated RNA?
    Author: Ishii KJ, Akira S.
    Journal: Immunity; 2005 Aug; 23(2):111-3. PubMed ID: 16111629.
    Abstract:
    CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, Kariko et al (2005) suggest that the innate immune recognition of RNA by TLR3, TLR7, or TLR8 is in fact controlled by modification of nucleotides, including methylation.
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