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  • Title: [Efficacy of keppra in combined therapy in pharmacoresistant adult epilepsy patients].
    Author: Karlov VA, Vlasov PN.
    Journal: Zh Nevrol Psikhiatr Im S S Korsakova; 2005; 105(7):38-44. PubMed ID: 16117145.
    Abstract:
    There were analyzed efficacy of keppra (Levetiracetam) in combined therapy in 31 patients with pharmacoresistant partial epilepsy and in 2 cases with idiopathic generalized epilepsy. During the 4 months 48.4% experienced at least a 50% reduction in the frequency of partial-oncet seizures, 12.9% at least a 75% reduction, and 25.8% demonstrated a seizure free. The combined therapy was ineffective only in 12.9%. The authors emphasize a good tolerability of keppra. There was only one case with side-effect, that demand cancel of Levetiracetam. The results obtained reveal effectiveness of keppra using in epileptology, in particular, in pharmacoresistant epilepsy.
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