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Title: Sodwanone S, a triterpene from the marine sponge Axinella weltneri. Author: Funel-Le Bon C, Berrué F, Thomas OP, Reyes F, Amade P. Journal: J Nat Prod; 2005 Aug; 68(8):1284-7. PubMed ID: 16124780. Abstract: The bioassay-guided fractionation of the crude extract of the marine sponge Axinella weltneri led to the isolation and the identification of a new triterpene named sodwanone S (1), with an uncommon oxepane-cyclohexane system, along with the known sodwanones A and G. The structure was elucidated using spectroscopic data, and the biological activity was evaluated against 13 human tumor cell lines. A biogenetic pathway of this new compound is also proposed.[Abstract] [Full Text] [Related] [New Search]