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  • Title: Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy.
    Author: Kinjo K, Sato H, Sakata Y, Nakatani D, Mizuno H, Shimizu M, Nishino M, Ito H, Tanouchi J, Nanto S, Hori M, Osaka Acute Coronary Insufficiency Study (OACIS) Group.
    Journal: Am J Cardiol; 2005 Sep 01; 96(5):617-21. PubMed ID: 16125481.
    Abstract:
    We evaluated the interaction between inflammation and survival benefit from statin therapy in patients who had acute myocardial infarction. Although 1-year mortality did not differ between patients who used statin therapy and those who did not, among patients who had C-reactive protein (CRP) concentrations in the lower 2 tertiles (<2.9 mg/L), 1-year mortality was higher in patients who used statin therapy than in those who did not within the highest CRP-defined tertile (> or =2.9 mg/L). Statin therapy significantly decreased the hazard ratio for 1-year mortality in patients who had high CRP levels to approximately the hazard present for patients who had low CRP levels and did not receive statin therapy.
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