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  • Title: [Comparative efficacy of choline antagonists in chronic obstructive lung disease].
    Author: Pavlishchuk SA, Bolotova EV.
    Journal: Probl Tuberk Bolezn Legk; 2005; (7):37-9; discussion 39-40. PubMed ID: 16130427.
    Abstract:
    The efficacy of thiotropium bromide, 18 microg/day, versus ipratropium bromide, 160 microg/day, was studied in 20 patients with chronic obstructive lung disease (COLD) treated with a drug for 4 weeks. Clinical and spirographic parameters and arterial blood gas composition were determined. According to clinical and spirographic data, thiotropium bromide has some advantage over ipratropium. Both test drugs improved blood gas composition.
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