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  • Title: [Surgical treatment of myasthenia gravis associated with Graves's disease].
    Author: Itoh Y, Ohuchi M, Yoshida I, Ohmi M.
    Journal: Nihon Kyobu Geka Gakkai Zasshi; 1992 Apr; 40(4):587-91. PubMed ID: 1613289.
    Abstract:
    During past 30 years, we experienced 253 patients who underwent surgery for myasthenia gravis. Among these patients, 9 were associated with Graves' disease. No patients had thymoma. Five patients underwent thymectomy after they had become euthyroid by medical treatment, though four patients required subtotal thyroidectomy before thymectomy. One patient developed myasthenic crisis following thyroidectomy and was treated with respirator for 5 days. But thymectomy was performed without myasthenic crisis in these four patients between 25 days and 60 days after thyroidectomy. They have been doing well and no see-saw phenomenon was presented. Thymectomy is safe and effective even in the patients with Graves's disease, and we recommend to perform it after they become euthyroid by medical or surgical treatment.
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