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  • Title: [Detection of genital tract cytomegalovirus and Chlamydia trachomatis infection in patients with tubal pregnancy].
    Author: Jin H, Lin J, Xu K.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 2001 Oct; 36(10):600-2. PubMed ID: 16134522.
    Abstract:
    OBJECTIVE: To investigate the influence of genital tract cytomegalovirus and chlamydia infection on the incidence of tubal pregnancy. METHODS: Ninety-five women with tubal pregnancy (study group) and 42 women with ovarian cysts (control group) were selected for this study. Serum cytomegalovirus (CMV) IgM was identified by enzyme-link-immunosorbent-assay (ELISA). Cervical secretions, endometrium, and salpinx tissue were tested for CMV gH gene and chlamydia heat shock protein (HSP) gene by nest polymerase chain reaction (PCR) and PCR respectively. RESULTS: CMV IgM was positive in 14 (15%) women with tubal pregnancy, and 1 (2%) in the control group. CMV gH gene was detected in 18 women (19%) and chlamydia HSP gene in 25 (26%) of the tubal pregnancy group, and 2 (5%) and 2 (5%) in the control group respectively. There were significant differences between the study and the control group (P < 0.05) with respect to detection of CMV IgM, CMV gH gene and chlamydia HSP gene. CONCLUSIONS: CMVand chlamydia trachomatis genital tract infection were more common in women with tubal pregnancy than that in the control group. Genital CMV and chlamydia trachomatis infection may associate with an increased incidence of tubal pregnancy.
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