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  • Title: [Randomized controlled study of S (+) -ismer of ibuprofen supporsitory].
    Author: You YH, Wu CL, Gao JS, Huang AL, Luo H.
    Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2004 Aug; 29(4):457-9. PubMed ID: 16134605.
    Abstract:
    OBJECTIVE: To evaluate the efficacy and safety of S (+) - ismer of ibuprofen supporsitory. METHODS: One hundred and three cases of postopterative pain and 60 cases of fever, altogether 163 patients were randomly divided into 2 groups: S (+) -ismer of ibuprofen supporsitory treatment group (one supporsitory per day for 3 days) and ibuprofen supporsitory treatment group (one supporsitory per day for 3 days). The therapeutic effect was assessed and the side-effects were observed between the 2 groups. RESULTS: After being given medicine in the first 4 hours, pain intensity difference, pain remission degree and the dropped level of fever in S (+) -ismer of ibuprofen were all bigger than those of the ibuprofen supporsitory treatment group. There was no difference in side-effects between the 2 groups. CONCLUSION: Therapeutic effect of S (+) -ismer of ibuprofen supporsitory is definite, whose action appears more quickly and stronger and it has fewer side-effects than those of ibuprofen supporsitory.
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