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  • Title: Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.
    Author: Witek B, Ochwanowska E, Rafay J, Kolataj A, Chrenek P, Suvegova K, Jurcik R, Sirotkin A, Darlak K.
    Journal: Neuro Endocrinol Lett; 2005 Aug; 26(4):397-400. PubMed ID: 16136002.
    Abstract:
    OBJECTIVES: Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight. METHODS: In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined. RESULTS: As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly. CONCLUSION: Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.
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