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  • Title: Blood flow and metabolic therapy in CNS injury.
    Author: Robertson CS, Goodman JC, Grossman RG.
    Journal: J Neurotrauma; 1992 May; 9 Suppl 2():S579-94. PubMed ID: 1613815.
    Abstract:
    A hypermetabolic state, consisting of increased resting energy expenditure, excessive protein wasting, and hyperglycemia, occurs in patients with a severe head injury. The hypermetabolism can affect survival by rapidly resulting in protein-calorie malnutrition (increased energy expenditure and protein wasting) and may adversely affect neurological recovery by altering the microenvironment of the injured brain (hyperglycemia).
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