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  • Title: [Comparison of clinical efficacy between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia].
    Author: Sun SP, Shang XJ, Huang YF.
    Journal: Zhonghua Nan Ke Xue; 2005 Aug; 11(8):621-3. PubMed ID: 16138585.
    Abstract:
    OBJECTIVE: To compare the clinical efficacy and safety between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia. METHODS: 86 patients with oligoasthenospermia were received at our clinic of andrology. They were randomly divided into group A and B. The patients in group A received Huorongbushen 48 g daily for 3 months, and the other patients in group B were given indomethacin 50 mg daily for 3 months. The sperm parameters of the patients were analyzed by computer-assisted sperm analysis system before and after treatment. RESULTS: Patients of group A were significantly improved in sperm concentration, forward sperm motility, total sperm motility, straight line velocity and average path velocity. Patients of group B remained unimproved in sperm concentration and were significantly improved in other sperm parameters. The patients in group A reported a significantly higher sperm concentration than that in group B. There was no significant difference between group A and B in other sperm parameters. CONCLUSION: Compared with indomethacin, Huorongbushen is efficacious for oligoasthenospermia with lower side effects.
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