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  • Title: Chaperomics: in vivo GroEL function defined.
    Author: Ellis RJ.
    Journal: Curr Biol; 2005 Sep 06; 15(17):R661-3. PubMed ID: 16139196.
    Abstract:
    A recent proteome analysis of protein folding inside cells of Escherichia coli predicts that only 84 of the approximately 2400 cytosolic proteins expressed in minimal media depend absolutely on the GroEL/GroES chaperone system to avoid aggregation. These proteins are enriched in alpha/beta domains and 13 are essential for growth.
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