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  • Title: Short-term memory in children with sickle cell disease: executive versus modality-specific processing deficits.
    Author: Schatz J, Roberts CW.
    Journal: Arch Clin Neuropsychol; 2005 Dec; 20(8):1073-85. PubMed ID: 16139469.
    Abstract:
    Prior research has identified a number of areas of cognitive deficit among children with sickle cell disease (SCD), including decrements in memory span and working memory. The present study examined short-term memory span and working memory performance among children with SCD (n = 25) and demographically matched comparison children (n = 25) using digit span, spatial span, and the self-ordered pointing test. Children with SCD showed difficulties only for digit span-backward. Additional cognitive ability measures administered indicated auditory processing was an area of deficit related to digit span-backward performance. The study suggests that modality specific deficits are one factor in short-term memory span for children with SCD. The cause of this deficit is unclear, but may involve both central and peripheral components of auditory processing.
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